Medizin
By Andrii Holovko
17 min read

A colorless liquid in a standard 1-liter bottle, with a slightly fruity-sweet smell, dissolving in seconds what other products take minutes to dissolve. Acetone, also known as propanone, dimethyl ketone, or 2-propanone, is an organic compound and the simplest ketone. Anyone who knows this substance only from the bathroom - as the unavoidable companion of nail polish removers - greatly underestimates it. Acetone is one of the world's most widely used chemical helpers: in laboratories, doctors' offices, electronics workshops, on construction sites, and at home on the desk.

In this article, you will learn everything you need to know about acetone as a solvent: from its fascinating history and most important areas of application to practical tips for safe use. And you will discover that this unassuming solvent has literally helped write human history.

What is acetone? Chemistry explained clearly

What is acetone? Chemistry explained clearly

Acetone has the chemical formula (CH₃)₂CO and is the simplest ketone. With its carbonyl group and two methyl groups, it is an important organic solvent in industry, households, and laboratories. That may sound rather dry at first - but behind this simple molecular structure lies an exceptional property: acetone has a rare dual solvency. It can dissolve both polar and nonpolar substances - a capability that many other solvents do not offer in this combination.

Acetone is a colorless, low-viscosity liquid with a characteristic odor; it is highly flammable and forms an explosive mixture with air. Its boiling point at normal pressure is 56 °C. It is miscible with water and most organic solvents in all proportions. This combination - strong solvency, complete water solubility, and rapid evaporation - makes acetone a true all-rounder that no other solvent can completely replace in this combination. Due to its high vapor pressure, it also evaporates extremely quickly.

Where does acetone occur in nature?

Anyone who thinks acetone is purely an industrial product is mistaken. The human body produces acetone as part of fat metabolism. It is also formed when fruit ferments and is a component of many plant-based flavorings. Small traces can also be detected in milk and some types of wood. The molecule is therefore anything but foreign to the body - it is part of our everyday biochemistry, long before we consciously put it to use.

How is acetone produced industrially?

Today, acetone is produced on an industrial scale from benzene and propene via the cumene hydroperoxide process, also known as the Hock phenol synthesis. It has thus become one of the most important solvents in the paint and polymer industries. Several million tons are produced worldwide each year - a clear sign of how indispensable this substance is to the modern economy.

From discovery to the First World War: The history of acetone

From discovery to the First World War: The history of acetone

Anyone who believes acetone is a modern invention will be corrected by history. Acetone was first discovered in 1606 by Andreas Libavius, when he heated lead(II) acetate. Later, in 1661, Robert Boyle produced acetone from wood vinegar, obtained through the dry distillation of wood. For centuries, acetone remained a substance that chemists knew and used but that played no particularly significant role in the world.

That changed abruptly with the outbreak of the First World War.

The Weizmann process: How acetone influenced the course of a world war

During the First World War, biochemist Chaim Weizmann made a contribution to the British munitions industry that proved decisive to the war effort. It urgently needed acetone as an essential component of cordite - the smokeless propellant without which British artillery would not have been able to fire. Weizmann developed a biotechnological process for obtaining the solvent from corn.

In 1912, Weizmann, a biochemist at the University of Manchester, discovered that the bacterium Clostridium acetobutylicum could ferment corn starch into acetone. When Britain’s acetone supplies - imported mainly from Germany before the war - collapsed at the beginning of the war, Winston Churchill personally turned to Weizmann. In May 1915, after Weizmann demonstrated to Churchill and the Admiralty that he could convert 100 tons of grain into twelve tons of acetone, the government requisitioned brewery and distillation facilities. Factories were built, and together they produced more than 90,000 gallons of acetone per year - enough to meet the seemingly insatiable demand of cordite production.

This event also marks the first industrial use of biotechnology in history - a remarkably modern idea for 1915. Weizmann’s work on acetone was fundamental to the outcome of the First World War. At the same time, it was the first application of industrial biotechnology - the use of biological systems to manufacture valuable products on an industrial scale, as is now widespread in the production of medicines and vaccines.

From the war economy to modern chemistry

Until the middle of the 20th century, acetone-butanol fermentation was an important method for producing acetone. The anaerobic bacterium Clostridium acetobutylicum was used for industrial production. With the development of petrochemical processes, fermentation was eventually replaced by more efficient chemical syntheses. But the solvent itself remained: It was not needed less, but more - and its applications continued to grow with every new industrial era.

Acetone uses: 10 clever applications at a glance

Enough history - let’s get to the practical side. Whether you want to use acetone in the household, work with it professionally, or are simply curious about what is possible: The following ten applications showcase the full range of this remarkable solvent. One thing always applies: High-quality products are essential. For all the applications described, you should use acetone with at least 99.5% purity - because impurities can not only reduce its effectiveness but also leave unwanted residue.

Application 1: Nail polish and cosmetics - the classic

Application 1: Nail polish and cosmetics - the classic

Let’s start with the best-known use. Many people encounter this chemical compound in everyday life: as nail polish remover or for removing stubborn adhesive residue. However, those who reach for ready-made nail polish remover at the drugstore usually get a diluted mixture with additives. By contrast, using pure acetone 99.5% delivers significantly faster and more thorough results - especially with stubborn gel polish or Shellac, which requires a longer exposure time under aluminum foil.

Practical tip: For gel nails, soak a cotton pad in acetone, place it on the nail, and secure it with aluminum foil for five to ten minutes. The gel polish will then come off completely without any residue - with no aggressive scraping.

Application 2: Removing adhesive residue, labels, and superglue

Everyone knows the situation: a price tag that will not come off cleanly. A drop of super glue that has hardened on the tabletop. Acetone is itself a solvent in many all-purpose and super glues. Conversely, this means it can also dissolve these adhesives. A cloth soaked in acetone, placed on the affected area briefly, will in most cases do what would otherwise take hours of scraping and rubbing.

Practical tip: Before using it on sensitive surfaces (paintwork, plastics), always test it first in an inconspicuous area. Acetone dissolves plasticizers and additives from many plastics, which can make the plastic brittle and sensitive.

Application 3: Degreasing and cleaning before painting

Anyone who has ever applied paint that peeled off again after a short time knows the problem: the surface was not clean enough. Grease, oil, silicone traces - even the finest residues prevent good paint adhesion. Painters and paint technicians use acetone when they want to remove old layers of paint or thoroughly prepare surfaces.

Acetone dissolves paints, oils, fats, resins, vinyl resins, asphalt, cellulose acetate, and nitrocellulose - an impressive range. For painters, auto body technicians, and woodworkers, the acetone cleaning ritual is therefore indispensable before applying paint. The result: better adhesion, a more even surface, and a longer-lasting coating.

Application 4: Cleaning electronics and circuit boards

Application 4: Cleaning electronics and circuit boards

Anyone who repairs or builds electronics knows: dirt and grease on circuit boards can cause short circuits and weaken solder joints. In photochemical circuit board manufacturing, acetone is used for the final cleaning of circuit boards - it removes flux residues and fingerprints. Electronics technicians use it for the same reason, to thoroughly clean circuit boards before soldering.

Why acetone in particular? Because it evaporates quickly, leaves no residue, and reliably dissolves fats and resins. For this application, a purity of 99.5% is especially important: impurities could deposit on sensitive contact surfaces and jeopardize the function of the components.

Caution is also required with the plastic housings of capacitors or relays - these can be softened or damaged by acetone.

Application 5: Degreasing metal in workshops and industry

Acetone is used to dissolve paint coatings and remove paint residues. It can also be used to degrease and clean metal machine parts and plastics that are inert to acetone. In automotive workshops, metalworking companies, and precision mechanics, degreasing workpiece surfaces before welding, bonding, or coating is a standard operation - and acetone is one of the most reliable agents for this purpose.

Practical tip: In construction and skilled trades, acetone is also used to clean and prepare joint edges and remove sealant residues. If silicone or PU foam residues need to be removed from tools or surfaces, it is best to use them while still fresh (not yet cured) and treat the areas immediately with acetone.

Application 6: Laboratory glass cleaning - precise and residue-free

In laboratories worldwide, acetone is indispensable in daily laboratory work. Anyone preparing glass vessels for analytical measurements knows that even tiny residues of water, grease, or previous substances can distort measurement results. Acetone reliably dissolves these contaminants, evaporates completely, and leaves no traces. Acetone is particularly important for sample preparation and as a rinsing liquid for cuvettes.

In practice, glass vessels are briefly rinsed with acetone after cleaning - this displaces residual water and dries the surface within seconds. For this application, the purity of 99.5% is absolutely crucial: Every contaminant is introduced directly into the vessel and can affect subsequent experiments.

Buy Acetone 99.5% Solvent 1000ml at Medicalcorner24 - grease-dissolving, residue-free

Application 7: Dental practice and medical applications

Anyone visiting their dentist may not realize that acetone plays a role in the treatment room. Special acetone-containing cleaning solutions are used here: They serve to clean, degrease, and dry prepared dentin surfaces, cavities, tooth stumps, root canals, crowns, bridges, as well as brackets and bands. This ensures optimal adhesion of filling materials and adhesives. In addition, acetone plays an important role in laboratories and the medical industry - for example, in extracting active ingredients or as a reagent in diagnostic tests. For medical professionals, dental practices, and laboratories, the purity of the acetone used is therefore particularly important: Only a highly pure solvent can deliver reproducible, reliable results.

Application 8: Wood restoration and conservation

In restoration and monument conservation, acetone is a proven tool - one that requires targeted use, however. For restoration purposes, acetone can be used in the controlled drying of damp wood, as well as for removing resins, fats, and asphalt and for cleaning glass, ceramics, iron, paper, and stone. The literature also cites the removal of black spots on bronze, residues from adhesive joints, and the separation of papers bonded with resin as examples of its use. Acetone is used especially in museums and workshops for antique furniture to dissolve old resin layers and impurities from wooden surfaces before a new treatment is applied. Important: Acetone should be used selectively and in small quantities, as it can also attack paints and pigments. Note for leather: Caution is required with genuine leather - leather contains natural oils that keep it supple. Acetone can remove these oils, leading to dryness and cracking. More suitable specialized products are available for leather.

Application 9: 3D printing and plastics processing

One of the most modern applications is so-called acetone vapor smoothing in 3D printing. The process is remarkably simple: A 3D-printed object made of ABS is exposed to acetone vapors in a sealed container. These slightly melt the outermost layer, causing the visible print lines to fuse together. The result is a smooth, glossy, almost injection-molded surface. Important: This process works only with ABS and ASA plastics. PLA, on the other hand, cannot be smoothed with acetone. But even beyond 3D printing, acetone is indispensable in plastics processing: In the chemical industry, it plays a key role in the production of PMMA (acrylic glass, Plexiglas). We encounter this material every day: in watch crystals, protective screens, medical devices, and design objects.

Application 10: Acetone in the human body - medical relevance

Perhaps the most surprising "application" of acetone takes place without any action on our part - inside the human body. In medicine, acetone is classified as one of the so-called ketone bodies. It is produced as an intermediate product during fat burning and is normally broken down by the metabolism. As part of the keto diet, more and more people are consciously using this biochemical mechanism: When the body is deprived of carbohydrates, it switches to burning fat - and in the process produces ketone bodies, including acetone, which is released through the exhaled air. In clinical diagnostics, elevated acetone levels in the blood or urine are an important warning sign: Acetone is produced as a metabolic byproduct in the human body and is excreted in the urine. Patients with severe diabetes mellitus develop acetonuria as an accompanying symptom and excrete up to 50 g of acetone per day. Important distinction: This medical relevance does not, of course, mean that industrial acetone should be ingested or used for self-medication. Buying acetone as a solvent means using it externally, while observing all safety rules.

Using acetone safely: What you absolutely need to know

As versatile as acetone is, it should be handled with due care. Anyone who knows the most important rules can work safely and effectively.

Fire protection and storage

Acetone has a boiling point of 56 °C and is highly flammable. This means that even at room temperature, acetone forms vapors that can combine with air to create an explosive mixture. Acetone is extremely flammable. Keep it away from open flames, sparks, and other ignition sources. Do not smoke near areas where acetone is being used, and take measures to prevent electrostatic discharges. For storage: Always keep acetone in tightly closed containers in cool, dry, and well-ventilated places. Avoid storing it near food and keep acetone away from children.

Protective equipment: What you should wear

Despite its low toxicity, acetone severely dries out the skin; therefore, hands and fingers should always be protected. Although acetone is generally considered relatively harmless, users should ensure adequate ventilation. It is also advisable to wear protective gloves - acetone quickly strips the skin of its natural moisture. An important note when choosing gloves: Acetone is inadequately retained by latex and vinyl gloves and may attack these materials - therefore, choose nitrile gloves, which offer significantly better protection. For the eyes, sealed safety goggles are recommended, especially when working with larger quantities.

Ventilation and first aid

The vapors can cause dizziness and fatigue with prolonged exposure. Due to its degreasing effect, acetone can make the skin dry and cracked. Therefore, always work in well-ventilated rooms or outdoors. In the event of accidental skin contact: immediately remove contaminated clothing and wash the affected area thoroughly with water. In case of eye contact, rinse the eyes with water for at least 15 minutes and seek medical attention. If acetone vapors are inhaled, the affected persons should immediately be taken to fresh air. Persistent symptoms should always be evaluated by a doctor.What should you look for when buying acetone?

What should you look for when buying acetone?

Not all acetone is the same - and for professional applications, purity makes the crucial difference. Technical acetone, which is sometimes found in hardware stores, may contain traces of water, methyl ethyl ketone, or other organic impurities. These additives are often tolerable for simple cleaning tasks - but are absolutely unsuitable for laboratory work, medical applications, or electronics cleaning.

Purity level: What does 99.5% mean?

A purity level of 99.5% means that a maximum of 0.5% of the liquid consists of other substances - water, aldehydes, and organic by-products. This may sound marginal, but it is not: particularly in analytics, dentistry, or electronics manufacturing, these 0.5% can make the difference between a perfect result and an incorrect measurement or connection. High-purity acetone with a concentration of 99.5% is synthetically produced, has an effective cleaning and degreasing effect, is used in electronics, precision engineering, optics, and industry, and evaporates quickly and without residue.

Packaging size and practicality

For occasional household use, small quantities are sufficient. However, anyone who works with it regularly - as a tradesperson, laboratory technician, dental assistant, or in an automotive workshop - is much better served with a 1-liter bottle. It offers good value for money, is easy to handle, and can be stored safely.

Our recommendation for all applications

Anyone looking for a reliable, high-quality solvent suitable for all the applications described in this article will find exactly what they need in the MC24 Acetone 99.5% Solvent 1000ml at Medicalcorner 24: synthetically produced, dissolves grease, evaporates without residue - and at a fair price. Whether at home, in the workshop, laboratory, or medical practice: this all-rounder performs well in any setting.

Conclusion: One solvent for almost everything - when quality is right

Acetone is far more than a nail polish remover. It is a chemical all-rounder with an impressive history dating back to the early 17th century and even influencing the course of a world war. From cosmetics and highly precise dental practices to the innovative world of 3D printing - hardly any other solvent combines such a broad range of applications with such good environmental compatibility.

The key to success in all these areas is purity. Only high-quality Acetone 99.5% truly evaporates without leaving residues, delivers maximum dissolving power, and produces reliable, reproducible results. It is the invisible yet indispensable foundation of quality for professionals.

For anyone who needs to rely on their material, MC24 Acetone 99.5% Solvent is the right choice. It stands for precisely this dependable purity and helps you complete your work accurately and cleanly - whether in the laboratory, workshop, or at home.

FAQ: Frequently asked questions about acetone

What is acetone and what is it used for?

Acetone (chemical formula: (CH₃)₂CO) is the simplest ketone and a colorless, highly volatile organic solvent with a characteristic fruity-sweet odor. It is one of the most widely used solvents worldwide and is used in a remarkably broad range of applications: at home for removing nail polish and adhesive residues, in trades for preparing surfaces before painting, in industry for degreasing metal, in laboratories for cleaning glassware, in dental practices for cleaning and degreasing dentin surfaces, and in plastics processing - for example, to smooth 3D-printed objects made of ABS. Acetone is fully miscible with water, evaporates without leaving residues, and dissolves both polar and nonpolar substances. This combination makes it unique among common solvents. In medicine, acetone is also known as a ketone body produced during fat metabolism in the human body - a sign that the substance is not only important industrially but also biologically.

Is acetone dangerous to your health?

Compared with many other organic solvents, acetone is considered relatively low in toxicity - it is not a carcinogen or mutagen, and the body even produces it in small amounts. Nevertheless, it should be handled with respect. The main risks: Acetone is highly flammable and produces vapors at room temperature that can form explosive mixtures with air. Prolonged skin contact removes natural fats and oils from the skin, causing dryness and irritation. Inhaling large amounts of acetone vapors can cause dizziness, drowsiness, headaches, and, in extreme cases, unconsciousness. For safe handling: Always work in well-ventilated areas, wear nitrile protective gloves, use safety goggles, and keep open flames and sparks away. Always follow the information on the product label and consult a doctor or safety officer if needed.

What difference does the purity grade make for acetone?

The purity grade of acetone is not merely a marketing feature - it directly affects the application result. Technical-grade acetone (often with 95-98% purity) contains water, methyl ethyl ketone, or other organic impurities. These may be tolerable for simple household cleaning tasks, but can become problematic in professional applications: In electronics cleaning, residues can cause corrosion on contact surfaces. In the laboratory, impurities can distort analytical results. In dentistry, insufficient purity can impair the adhesion of fillings and brackets. In 3D-printing smoothing, contaminated acetone can create uneven surfaces. By contrast, a purity grade of 99.5%, as with MC24 acetone, guarantees completely residue-free evaporation and maximum dissolving power - for professional results in every field of application.

Can acetone be used to clean medical instruments?

Acetone is indeed used in medical and dental facilities - but for very specific tasks and not as a general disinfectant. Solutions containing acetone are used in dentistry to clean prepared dentin surfaces and root canals, as well as to degrease tooth stumps, crowns, and brackets before bonding. It reliably removes fats, oils, and moisture from surfaces, thereby improving the adhesion of adhesives and composite materials. However, acetone is not suitable as a fully effective disinfectant - that is, for killing germs, bacteria, or viruses. Special disinfectants based on alcohol (e.g., isopropanol or ethanol) or aldehyde-containing compounds are used to disinfect medical instruments. For medical applications, always follow the manufacturer's instructions and consult a doctor or pharmacist if necessary.

What is the difference between acetone and isopropanol?

Acetone and isopropanol are both organic solvents and are frequently used for cleaning and degreasing - but they have different strengths. Acetone is a ketone ((CH₃)₂CO) and a significantly stronger solvent than isopropanol. It dissolves resins, paints, plastics such as polystyrene, adhesives, and fats particularly effectively. At the same time, it can attack certain plastics and paints, which is why a material compatibility test is recommended before use. Isopropanol (IPA, 2-propanol) is milder, dries out the skin less, and can be used safely on significantly more surfaces. It is also effective as a disinfectant against bacteria, fungi, and many viruses - a property that acetone does not have. In short: For disinfection → isopropanol. For powerful dissolving and degreasing tasks → 99.5% acetone. Both products complement each other ideally in professional use.

Where can you buy acetone in Germany?

Acetone is available in Germany from drugstores, hardware stores, pharmacies, and online - although the quality varies considerably. Drugstores usually sell diluted nail polish removers with additives, which are unsuitable for professional applications. In hardware stores, acetone is often available as a technical solvent with a lower degree of purity. If you want to buy high-purity 99.5% acetone online - for laboratory, medical practice, craft, or industrial use - specialized online shops are a much better option. Medicalcorner 24 offers MC24 Acetone 99.5% in the practical 1-liter bottle at a fair price, with fast shipping to Germany, Austria, and Switzerland. Purchasing from a specialist supplier ensures not only the correct purity, but also proper labeling, a safety data sheet, and secure packaging for transport.

Is acetone really produced in the human body?

Yes - and this is one of the most fascinating aspects of this solvent. Acetone is one of the so-called ketone bodies, which are synthesized in the liver from fatty acids. Normally, these ketone bodies are further metabolized in the body and provide energy - especially for the brain and heart. Acetone is produced as a by-product and is excreted mainly through the breath and urine. Under normal circumstances, the amounts are so small that they are barely noticeable. However, on a low-carbohydrate diet (ketosis, ketogenic diet), ketone production increases sharply - many people then notice a slightly sweet or fruity, acetone-like odor on their breath. In cases such as poorly controlled type 1 diabetes mellitus, acetone production can increase so much that patients excrete up to 50 g per day - a medical emergency known as diabetic ketoacidosis. Please consult a doctor immediately if you experience corresponding symptoms.

Where can I find further scientifically sound information about acetone?

This article is based on reviewed specialist chemical literature and public databases. If you would like to explore the subject in greater depth, the following authoritative sources are recommended:


About Andrii Holovko

Andrii Holovko is an analyst with a university education in computer science, library science, and pedagogy. Thanks to his experience in public relations (PR) and many years of work in the IT industry, he writes expert articles on current topics, based on in-depth analyses and up-to-date scientific sources. His current professional focus is on creating high-quality content (content creation) and online marketing.